
United trounced the Giallorossi 7-1 last season, but don't expect the Italian defence to ship quite so many this time around. With a home win already on the board, there's no pressure on Roma to get anything out of Tuesday night's match. The visitors might even play for a draw.
Form guide: Roma won their opening Group F match against Dynamo Kyiv 2-0, with goals from Francesco Totti and Simone Perrotta. However, Luciano Spalletti's team arrive in Manchester on the back of a 4-1 loss to Inter Milan, which leaves them fourth in Serie A. Meanwhile, United's march up the Barclays Premier League table continued with a 1-0 win against Birmingham on Saturday. Cristiano Ronaldo scored the winner, just as he did on Matchday 1 at Sporting Lisbon.
Ins and outs: The Italians have picked up a number of injuries in recent weeks, with Marco Cassetti (thigh), Francesco Totti (thigh) and Alberto Aquilani (ankle) the most high-profile. Totti and Aquilani should be available on Tuesday, but Cassetti has been ruled out for a month. Nemanja Vidic and Wes Brown are doubtful for United, while goalkeeper Edwin van der Sar (toe) will be replaced by Tomasz Kuszczak.
Star men: European Golden Shoe winner Francesco Totti has started strongly once again, scoring four goals in his last five league appearances. Meanwhile, Michael Carrick will be hoping for a similar performance to the one he produced in April's 7-1 demolition.
Wayne Rooney knows precisely how determined AS Roma will be to exact revenge on United after the Reds' 7-1 victory back in April – because he has put himself in their shoes.After thrashing the Italians in the Champions League quarter final second leg last season, the Giallorossi return to Old Trafford in Tuesday's Group F clash hell-bent on setting the record straight.
Rooney has been deployed as the main striker in United's attack this season, with Carlos Tevez dropping deeper. When asked to do a similar job last season, he went on a scoring run of 11 goals in 14 matches during March and April. He will be hoping to do that again, and says his partnership with Tevez has plenty of potential.
Skipper raring for return